Drug Efficacy Test
An innovative genetic test that helps personalise treatment based on a patient’s genetic profile. It analyses genes that influence drug absorption, effectiveness, and the risk of adverse reactions – supporting safer and more effective therapy.
Effective treatment starts with your genes
Even with the same diagnosis, different people may require completely different treatment pathways. Genetic differences determine how the body absorbs, metabolises, and responds to medications – what works well for one person may not work for another, or may cause side effects. Pharmacogenetic testing evaluates medication response based on your DNA so that treatment can be personalised, safe, and effective from the start – without trial and error.
Which genes are analysed in a pharmacogenetic test?
Pharmacogenetic testing helps assess how your body metabolises and responds to different medicines. Even a standard dose can have very different effects from person to person due to genetic differences. The test analyses genes linked to enzyme activity responsible for drug metabolism, effectiveness, and potential side effects. With this information, treatment becomes targeted and individualised. The test evaluates:
Activity of enzymes involved in drug metabolism (e.g., CYP2D6, CYP2C19, CYP3A4, etc.)
Risk of adverse drug reactions
Genetically determined drug effectiveness
Drug interactions in polypharmacy
Individual dosing requirements
Key therapeutic areas: psychiatry, neurology, cardiology, oncology, pain management, and others.
Personalised treatment: when medications are chosen based on your DNA
Pharmacogenetic testing helps select the most suitable medicines and doses based on your genetic profile. This helps avoid adverse effects, increases treatment effectiveness, and reduces the time spent searching for the right medication.
A more effective treatment plan
Helps the doctor choose the medication most likely to work for you, based on genes that affect drug metabolism.
Lower risk of side effects
Your genetic profile can reveal which medications may cause adverse reactions – or may even be unsafe for your body.
A faster path to effective treatment
Instead of trial and error, a more direct route to treatment that works – especially important for chronic or complex conditions requiring combinations of medicines.
More appropriate dosing
Based on enzyme activity levels, the dose can be adjusted to achieve optimal effect with minimal risk.
When and for whom is the test recommended?
For people taking multiple medications
Helps assess how drugs may interact and supports avoiding unnecessary complications.
For those experiencing weak or adverse medication effects
If medicines do not work as expected or cause side effects, genetic testing can help explain why.
For those with a family history of medication-related adverse events
If family members have experienced severe side effects or allergic reactions, it may be worth evaluating your genetic predispositions.
For people with chronic illnesses
Helps choose a safer and more effective long-term treatment plan.
“Pharmacogenetic testing helps objectify medication selection strategies, especially in psychiatry, where many diagnoses are primarily based on clinical symptoms rather than instrumental tests.”
Pharmacogenetic test reliability: accuracy and quality metrics
The pharmacogenetic test analyses up to 21 genes that influence drug metabolism and response. Based on these data, clear, evidence-based recommendations are provided for medication selection and dosing. The test is performed safely and conveniently from a saliva sample.
99% genotype calling accuracy
Analysis of 120+ active pharmaceutical ingredients
10,000+ samples used for reliability validation
A genetically informed treatment plan
Take the pharmacogenetic test and receive medication recommendations tailored specifically to you.
For Specialists
All key information in one place – from the genes analysed to test accuracy and clinical value. This section is intended for specialists who want a detailed understanding of the test rationale, structure, and practical applications.
The test includes key pharmacokinetic and pharmacodynamic genes such as CYP2D6, CYP2C19, CYP2C9, CYP3A4, CYP3A5, COMT, VKORC1, SLCO1B1, and others.
These genes determine enzyme activity levels, which affect the speed of drug metabolism – from very slow to ultra-rapid. This helps adjust dosing and choose appropriate medications, avoiding lack of efficacy or toxic effects.
14-gene panel: covers core enzymes involved in the metabolism of commonly prescribed medications (analysis of ~262 active pharmaceutical ingredients).
21-gene panel: expands the analysis by including additional genes (e.g., DPYD, DRD2, GLP1R), enabling assessment of metabolic responses to specific drug groups (e.g., antipsychotics, chemotherapy agents).
This option is recommended for complex cases, polypharmacy, or when broader pharmacogenetic insight is needed.
Pharmacogenetic testing helps reduce the risk that psychotropic medications will be ineffective (40–70% of cases) or cause significant side effects (up to 7% of patients). It is particularly important for patients taking multiple psychotropic and/or additional somatic medications. The test supports personalised treatment, shortens the time required to find suitable medication, and helps avoid prolonged trial-and-error approaches.
The test helps identify patients for whom clopidogrel or warfarin may be ineffective due to reduced metabolism. For example, a CYP2C19 poor metaboliser may not respond to clopidogrel, while VKORC1 and CYP2C9 variants can increase bleeding risk when taking warfarin.
